Just like your body, your skin has its own immune system to protect against environmental threats, emotional stress, and aging, factors which not only weaken skin, but also damage its appearance.

This is not surprising as the body’s largest organ is the first line of defense against bacteria and other exogenous agents. The skin acts as a physical barrier to alleviate the work of the central immune system. And just as researchers have established links between our immune system and our general health, there is also an interaction between skin’s beauty and the condition of its immune system. But the cell that safeguards our skin’s immunity—the Langerhans cell—represents only 2% to 5% of the epidermis.

Shiseido discovered that the skin’s multi-defensive power—which protects it and maintains its balance, health, and beauty—is compromised by external aggressors, emotional stress, and aging.

The luxury skin-care brand has developed the first complex that directly targets Langerhans cells. It restores the Langerhans cell functions that have been weakened by environmental factors, aging, and emotional stress.

For Shiseido, there are three key elements to a healthy vibrant skin: clarity, hydration, and firmness.

The luxury skin-care brand has developed the first complex that directly targets Langerhans cells. It restores the Langerhans cell functions that have been weakened by environmental factors, aging, and emotional stress.

For Shiseido, there are three key elements to a healthy vibrant skin: clarity, hydration, and firmness.

Now there is a perfect solution: Ultimune is your skin’s guardian. It does so much more than just repair visible damage. It is the first product to reactivate the skin’s multi-defensive power to resist, protect, regenerate and strengthen against harmful aggressors. It is the power your skin needs to visibly slow down the ageing process for as long as possible.

It activates four powers within your skin: the power to RESIST, PROTECT, REGENERATE, and STRENGTHEN. With Ultimune, your skin rediscovers its ultimate, timeless beauty: perfect, flawless, trouble-free skin, glowing with health and free from all visible signs of aging.

Through Shiseido's exclusive skin science research, the brand has developed a holistic approach to channel these powers.

Your Defend + Regenerate skin-care routine centers on finding your skin's own natural defensive and regenrative powers as you massage these products to bring out your healthiest, most vibrant skin.